Cerezyme^® (imiglucerase for injection) is available by prescription only. Cerezyme is supplied as a sterile, non-pyrogenic, lyophilized product. It is available to healthcare providers as follows:

200 Units per Vial NDC 58468-1983-01
400 Units per Vial NDC 58468-4663-01

To order Cerezyme

Orders may be placed by calling toll free 1-800-745-4447.
Hours of operation are Monday - Friday, 8:00 a.m. to 6:00 p.m. EST, excluding holidays.

Please note that new customers must establish an account with Genzyme before orders may be shipped.*

The following information is needed to process your order:

Full Name

Telephone Number

Genzyme Account Number*

Purchase Order Number

Name of Product (ex: Cerezyme)

Strength of Product (ex: 400 unit vial)

Quantity of Product (ex: 5 vials)

A Customer Service representative within Genzyme Therapeutics will provide an order confirmation number when the order is placed. Please note that orders placed via fax or voice mail message should not be considered received until a confirmation number is provided.

To guarantee next day delivery, orders must be received by 5:00 p.m. EST, Monday through Thursday, excluding holidays.

*To establish an account with Genzyme Therapeutics, please call us toll free at 1-800-745-4447.

Contact us

For additional information regarding Cerezyme (imiglucerase for injection), please contact us:

Genzyme Therapeutics
500 Kendall Street
Cambridge, MA 02142

In the US & Canada: 1-800-745-4447
Outside the US & Canada: 617-768-9000
Email Us

Reimbursement information

To bill for Cerezyme therapy, the provider must use the appropriate codes. The billing procedures may vary according to the site of service or third-party payor guidelines.

Download Cerezyme Fact Sheet (PDF)
Download Cerezyme Billing Guide (PDF)

Important Safety Information

Approximately 15% of patients have developed immune responses (antibodies). These patients have a higher risk of an allergic reaction (hypersensitivity). Use Cerezyme® (imiglucerase for injection) carefully if you have had an allergic reaction to the product in the past. Symptoms suggestive of allergic reaction happened in 6.6% of patients, and include anaphylactoid reaction (a serious allergic reaction), itching, flushing, hives, an accumulation of fluid under the skin, chest discomfort, shortness of breath, coughing, cyanosis (a bluish discoloration of the skin due to diminished oxygen), and low blood pressure. Side effects related to Cerezyme administration have been reported in less than 15% of patients. Each of the following events occurred in less than 2% of the total patient population. Reported side effects include nausea, vomiting, abdominal pain, diarrhea, rash, fatigue, headache, fever, dizziness, chills, backache, and rapid heart rate. Because Cerezyme therapy is administered by intravenous infusion, reactions at the site of injection may occur: discomfort, itching, burning, swelling or uninfected abscess. Cerezyme is available by prescription only. For more information, consult your physician. To learn more, please see full product information (PDF), or contact Genzyme at 1-800-745-4447.