Cerezyme^® (imiglucerase for injection) is available by prescription only. Cerezyme is supplied as a sterile, non-pyrogenic, lyophilized product. It is available to healthcare providers as follows:

200 Units per Vial NDC 58468-1983-01
400 Units per Vial NDC 58468-4663-01

To order Cerezyme

Orders may be placed by calling toll free 1-800-745-4447.
Hours of operation are Monday - Friday, 8:00 a.m. to 6:00 p.m. EST, excluding holidays.

Please note that new customers must establish an account with Genzyme before orders may be shipped.*

The following information is needed to process your order:

Full Name

Telephone Number

Genzyme Account Number*

Purchase Order Number

Name of Product (ex: Cerezyme)

Strength of Product (ex: 400 unit vial)

Quantity of Product (ex: 5 vials)

A Customer Service representative within Genzyme Therapeutics will provide an order confirmation number when the order is placed. Please note that orders placed via fax or voice mail message should not be considered received until a confirmation number is provided.

To guarantee next day delivery, orders must be received by 5:00 p.m. EST, Monday through Thursday, excluding holidays.

*To establish an account with Genzyme Therapeutics, please call us toll free at 1-800-745-4447.

Contact us

For additional information regarding Cerezyme (imiglucerase for injection), please contact us:

Genzyme Therapeutics
500 Kendall Street
Cambridge, MA 02142

In the US & Canada: 1-800-745-4447
Outside the US & Canada: 617-768-9000
Email Us

Reimbursement information

To bill for Cerezyme therapy, the provider must use the appropriate codes. The billing procedures may vary according to the site of service or third-party payor guidelines.

Download Cerezyme Fact Sheet (PDF)

Important Safety Information

Adverse reactions related to Cerezyme® (imiglucerase for injection) administration have been reported in less than 15% of patients. Each of the following events occurred in less than 2% of the total patient population. Reported adverse events include nausea, vomiting, abdominal pain, diarrhea, rash, fatigue, headache, fever, dizziness, chills, backache, and tachycardia. Adverse events associated with the route of administration include discomfort, pruritus, burning, swelling or sterile abscess at the site of venipuncture. Symptoms suggestive of hypersensitivity include anaphylactoid reaction, pruritus, flushing, urticaria, angioedema, chest discomfort, dyspnea, coughing, cyanosis and hypotension. Approximately 15% of patients have developed IgG antibodies; periodic monitoring is suggested. Side effects should be reported promptly to Genzyme Medical Information at 800-745-4447, option 2. To learn more, please see full product information (PDF), or contact Genzyme at 1-800-745-4447.