Daily Life with Cerezyme

If you have Type 1 Gaucher disease, taking care of your overall health is especially important. Coping with Type 1 Gaucher symptoms like fatigue, pain, and changes in physical appearance may seem overwhelming at times. But, in addition to sticking with Cerezyme treatment, there are some simple steps you can take to help manage your symptoms. Maintaining a healthy weight, avoiding smoking, getting enough rest, and being as physically active as possible can help give you needed stamina and help minimize the impact Type 1 Gaucher disease has on your daily life. When your overall health is good, you may find that any Gaucher symptoms you have are easier to handle.

The information in this section is meant to help give you pointers on lifestyle changes that may be appropriate for you.

Talk with your doctor before starting an exercise program or changing your diet. Your doctor can help you develop a plan that meets your unique needs.

Indication & Usage

Cerezyme® (imiglucerase for injection) is indicated for long-term enzyme replacement therapy for pediatric and adult patients with a confirmed diagnosis of Type 1 Gaucher disease that results in one or more of the following conditions:

  1. anemia (low red blood cell count)
  2. thrombocytopenia (low blood platelet count)
  3. bone disease
  4. hepatomegaly or splenomegaly (enlarged liver or spleen)

Important Safety Information

Approximately 15% of patients have developed immune responses (antibodies). These patients have a higher risk of an allergic reaction (hypersensitivity). Use Cerezyme® (imiglucerase for injection) carefully if you have had an allergic reaction to the product in the past. Symptoms suggestive of allergic reaction happened in 6.6% of patients, and include anaphylactoid reaction (a serious allergic reaction), itching, flushing, hives, an accumulation of fluid under the skin, chest discomfort, shortness of breath, coughing, cyanosis (a bluish discoloration of the skin due to diminished oxygen), and low blood pressure.

Side effects related to Cerezyme administration have been reported in less than 15% of patients. Each of the following events occurred in less than 2% of the total patient population. Reported side effects include nausea, abdominal pain, vomiting, diarrhea, rash, fatigue, headache, fever, dizziness, chills, backache, and rapid heart rate. Because Cerezyme therapy is administered by intravenous infusion, reactions at the site of injection may occur: discomfort, itching, burning, swelling or uninfected abscess. Cerezyme is available by prescription only. For more information, consult your physician.

Please see Full Prescribing Information (PDF).

Cerezyme has been demonstrated for over 17 years to be an effective treatment for Type 1 Gaucher disease in adults and children.